Webinaire du CCEM: 'Electrochemical measurements for electrolytic conductivity and determination of biomarkers'
08 juin 2023
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Electrolytic conductivity measurements
Carsten Thirstrup (DFM)
Electrolytic conductivity is a widely used parameter for the characterization of purity of water and it is very sensitive to impurities and contaminants in water. Sensors based on electrolytic conductivity are widely used in diverse industries, including pharmaceuticals, food, power, manufacturing, and environmental monitoring. Direct traceability can be made to the SI-unit system in terms of geometric measurements of a (primary) electrolytic conductivity cell.
In the present talk, an introduction to electrolytic conductivity measurements will be presented, including various electrical and physical configurations of electrolytic conductivity cells, data modelling, traceability, and uncertainty computations. Measurements in the conductivity range from the level of ultra-pure water up to nearly saturated potassium chloride (KCl(aq)) covering almost 7 decades of conductivity will be treated. New trends in the design of commercial electrolytic conductivity sensors and the challenges they pose for metrology will also be discussed.
Voltammetric (Bio)Sensor and Device Production for the Determination of Biomarkers and Some Important Analytes,
Mustafa Çetintaş (TÜBİTAK UME)
There are many different techniques for the determination of some viruses and/or their specific fragments including spike and nucleocapsid proteins, some biomarkers pivotal for human health, and some toxic metals or organic/inorganic compounds, but electrochemical methods stand out in terms of cheapness, simplicity, speed, sensitivity and selectivity.
In this context, it was aimed the minimization, production and characterisation of the relatively macro-sized (bio)sensors in order to lessen the consumption of chemical materials, optimisation and formation of the measurement procedure, real sample application, design, production and verification of the mini-sized device performing the measurement.
As a result, various electrochemical (bio)sensors and a mini-sized, cheap and verified potentiostat/galvanostat were produced that could detect the specific antigen or antibody proteins of the SARS-CoV-2 in real and/or synthetic samples, antioxidants like quercetin, toxic compounds like hydrazine, and biomarkers like cortisol.
Presentations
Carsten Thirstrup (DFM)
