CCQM-K115
MEASURAND: Mass fraction of hCP
Degrees of equivalence Di and expanded uncertainty (k = 2) Ui expressed in mg/g.
CCQM-K115
MEASURAND: Mass fraction of overall peptide-related impurities
Degrees of equivalence Di and expanded uncertainty (k = 2) Ui expressed in mg/g.
CCQM-K115
MEASURAND: Mass fraction of hCP
Degrees of equivalence Di and expanded uncertainty (k = 2) Ui
expressed in mg/g.
Results are presented under A4 printable format in Summary Results (PDF file).
CCQM-K115
MEASURAND: Mass fraction of overall peptide-related impurities
Degrees of equivalence Di and expanded uncertainty (k = 2) Ui
expressed in mg/g.
Results are presented under A4 printable format in Summary Results (PDF file).
| Metrology area, Sub-field | Chemistry and Biology, Protein Analysis |
| Description | Peptide purity determination - synthetic human C peptide (HCP) |
| Time of measurements | 2014 |
| Status | Approved for equivalence |
| Final Reports of the comparisons | |
| Transfer device | Dedicated samples |
| Comparison type | Key Comparison |
| Consultative Committee | CCQM (Consultative Committee for Amount of Substance) |
| Conducted by | CCQM (Consultative Committee for Amount of Substance) |
| Comments | Classified as "Bionanalysis" until 15 January 2018
Results published on 09 February 2017 Peptide purity determination - synthetic human C peptide (HCP)
|
| Pilot institute |
BIPM
Bureau International des Poids et Mesures BIPM - International Organization |
| Contact person | R. Josephs +33 (0) 1 45 07 70 55 |
| Pilot laboratory | |
|---|---|
| BIPM |
Bureau International des Poids et Mesures, BIPM - International Organization, N/A |
| HSA |
Health Science Authority, Singapore, APMP |
| INMETRO |
Instituto Nacional de Metrologia, Qualidade e Tecnologia, Brazil, SIM |
| LGC |
Laboratory of the Government Chemist, United Kingdom, EURAMET |
| NIM |
National Institute of Metrology, China, APMP |
| NIMT |
National Institute of Metrology (Thailand), Thailand, APMP |
| NMIJ AIST |
National Metrology Institute of Japan, Japan, APMP |
| NMISA |
National Metrology Institute of South Africa, South Africa, AFRIMETS |
| NRC |
National Research Council, Canada, SIM |
| PTB |
Physikalisch-Technische Bundesanstalt, Germany, EURAMET |
| UME |
TÜBITAK Ulusal Metroloji Enstitüsü, Türkiye, EURAMET |
This page proposes print-out on A4 paper (portrait) of the comparison details (best printed out using a black and white printer).
Please, select items to be printed out, then click on "OK" :
CCQM-K115
MEASURAND: Mass fraction of hCP
|
The key comparison reference value, xR, and its associated standard uncertainty, uR, are computed as explained in page 30 of the CCQM-K115 Final Report.
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|
The degree of equivalence of each laboratory i with respect to the key comparison reference value is given by a pair of terms: Di = (xi - xR) and its associated expanded uncertainty (k = 2) Ui, both expressed in mg/g. Ui is caclulated as Ui = [ULabi2+(2uR)2]1/2. |
CCQM-K115
MEASURAND: Mass fraction of overall peptide-related impurities
|
The BIPM result has been adopted as the key comparison reference valus, xR, with its associated standard uncertainty, uR.
|
|
The degree of equivalence of each laboratory i with respect to the key comparison reference value is given by a pair of terms: Di = (xi - xR) and its associated expanded uncertainty (k = 2) Ui, both expressed in mg/g. Ui is caclulated as Ui = [ULabi2+(2uR)2]1/2. |
CCQM-K115
MEASURAND: Mass fraction of hCP
xi : result reported by laboratory i
ULab i : stated expanded uncertainty of xi (k = 2)
Mass Bal. : Mass Balance
PICAA : peptide impurity corrected amino acid analysis
CCQM-K115
MEASURAND: Mass fraction of overall peptide-related impurities
xi : result reported by laboratory i
ULab i : stated expanded uncertainty of xi (k = 2)
LC-hrMS : liquid chromatography/high resolution mass spectrometry
LC-CAD-UV : liquid chromatography/charged aerosol detector/ultra violet
ULC-tofMS : ultra performance chromotography time-of-flight mass spectrometry
LC-MS/MS : liquid chromatography/tandem mass spectrometry
LC-UV : liquid chromatography/ultra violet
